第五届单细胞与空间组学论坛1月5日，北京师范大学/军事医学科学院研究团队在期刊《Advanced Science》上发表了题为“NAD+-Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell ...

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. Researchers said the AI tool, ...

The protein community is awash in data. As of October, the UniProt database of protein sequences had more than 44 million entries. UniProt serves as a clearinghouse for sequences. Researchers who ...

Advances in genome sequencing and structural biology mean that we are now buried under an avalanche of predicted domains and structures of proteins with unknown functions. Two groups have used ...

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers said the AI tool, ...

The enzyme sirtuin 6, or SIRT6, serves many key biological functions in regulating genome stability, DNA repair, metabolism and longevity, but how its multiple enzyme activities relate to its various ...

Cravatt’s strategy for ferreting out new inhibitors for multiple enzymes simultaneously is a good example “of how a strong understanding of enzyme mechanisms can serve as a starting point for studies ...

A dawning field of research, artificial biology, is working toward creating a genuinely new organism. At Princeton, chemistry professor Michael Hecht and the researchers in his lab are designing and ...

In this corner: the state-of-the-art enzyme function prediction tool … the Bioinformatic Brawler … the Basic Local Alignment Search Tool for proteins … BLASTp! And in this corner: the contender … the ...

An artist's representation of leucyl-tRNA synthetase, which belongs to the Aminoacyl tRNA synthetase family, from bacteria Thermus thermophilus. The European Bioinformatics Institute Enzymes — ...